Protein ICAM2 map

Identifiers
HUGO:ICAM2

Maps_Modules
MODULE:INPUT_ACTIVATORS MODULE:TUMOR_RECOGNTITON MODULE:INTEGRINS

References
 NATURAL_KILLER  map
CASCADE:LFA1
PMID:20955708
ICAM2 is Associated With a Potential Anti-Tumor Immune Response in Early Intraepithelial Stages of Human Pancreatic Carcinogenesis.
The anti-tumor immune reaction changed from an immune response to immune tolerance between the stages of intraductal papillary mucinous adenoma (IPMA) and intraductal papillary mucinous carcinoma (IPMC).
Expression levels oF ICAM2 is up-regulated exclusively in IPMA and disappeared from IPMC.

Modifications:
In compartment: TUMOR_CELL_AS_INDUCTOR_Membrane
  1. ICAM2@TUMOR_CELL_AS_INDUCTOR_Membrane map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. DNAM1*|​pho@INNATE_IMMUNE_CELL_Membrane map + CD11a*:​CD18*@INNATE_IMMUNE_CELL_Membrane map → map CD11a*:​CD18*:​DNAM1*|​pho@INNATE_IMMUNE_CELL_Membrane map