Protein PTPRC
Identifiers
HUGO:PTPRC
Maps_Modules
MODULE:TUMOR_RECOGNTITON MODULE:NK_ACTIVATING_RECEPTORS
References
CASCADE:SLAMF7
NATURAL_KILLER
INPUT_ACTIVATORS
PMID:25312647
CD45 is required for the activating function of SLAMF7 but not of 2B4 in NK cells.
Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- PTPRC@INNATE_IMMUNE_CELL_Cytosol
Participates in complexes:
Participates in reactions:
As Reactant or Product:
As Catalyser:- SH2D1B@INNATE_IMMUNE_CELL_Membrane
+ s1747 →
SH2D1B|pho:SLAMF7|pho|hm2@INNATE_IMMUNE_CELL_Membrane