Protein TSC2 map

Identifiers
HUGO:TSC2

Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS

References
PMID:12906785, PMID:19022819
AKT activates Rapamycin associated protein FRAP2 ( mTOR ) probably through Tuberin/GTP-binding protein Ras homolog enriched in brain ( RHEB ) pathway.

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. TSC1:​TSC2@INNATE_IMMUNE_CELL_Cytosol map
  2. TSC1:​TSC2|​pho@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. TSC1:​TSC2@INNATE_IMMUNE_CELL_Cytosol map → map TSC1:​TSC2|​pho@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. (GTP:​RHEB)|​active@INNATE_IMMUNE_CELL_Cytosol map + GDP@INNATE_IMMUNE_CELL_Cytosol map → map GDP:​RHEB@INNATE_IMMUNE_CELL_Cytosol map + GTP@INNATE_IMMUNE_CELL_Cytosol map