Reaction state_transition re15
L-tyrosine@neuron + tetrahydrobiopterin@neuron + O2@neuron → L-dopa@neuron + 4a-hydroxytetrahydrobiopterin@neuron
Reaction regulators:

Catalysis

1. TYR@neuron
2. (Fe2+:​TH|​S19_pho)|​active@neuron