Reaction state_transition re410 map
isocitric acid@mitochondrial matrix map + NAD(+)@mitochondrial matrix map → 2-oxoglutaric acid@mitochondrial matrix map + NADH@mitochondrial matrix map + CO2@mitochondrial matrix map + H+@mitochondrial matrix map
Reaction regulators:
Catalysis
  1. Ca2+:​IDH3A:​IDH3B:​IDH3G:​Mn2+@mitochondrial matrix map
Trigger
  1. ADP@mitochondrial matrix map
  2. Ca2+@mitochondrial matrix map