Reaction state_transition re414
isocitric acid@mitochondrial matrix
+
NADP(+)@mitochondrial matrix
→
H+@mitochondrial matrix
+
NADPH@mitochondrial matrix
+
CO2@mitochondrial matrix
+
2-oxoglutaric acid@mitochondrial matrix
Reaction regulators:
Catalysis
IDH2:Mn2+@mitochondrial matrix
+ NADP(+)@mitochondrial matrix → H+@mitochondrial matrix + NADPH@mitochondrial matrix + CO2@mitochondrial matrix + 2-oxoglutaric acid@mitochondrial matrix