Reaction state_transition d_re5 map

gDeaminated_alkylated_mismatched_base*@Nucleus map → gBER_M-glyc_DNA_st2*@Nucleus map + Base@default map

Reaction regulators:
Catalysis
  1. UNG@default map
  2. MPG@default map
  3. SMUG@default map
  4. HUS1:​RAD1:​RAD9*|​pho:​TDG@default map
  5. RAD23*:​TDG:​XPC@default map
  6. MBD4:​MLH1@default map
Trigger
  1. ATRIP:​ATR|​pho@default map


References
9-1-1 complex activates TDG glycosylase and activates BER:
PMID:17855402
DNA with O6-methylguanine adducts, MutSalpha and MutLalpha activate ATR/ATRIP and BER pathways performs the repair:
PMID:16713580, PMID:18543256

Confidence
REF=3 FUNC=3