Reaction state_transition d_re222 map

TP53BP1@default map → TP53BP1|​pho@default map

Reaction regulators:
Catalysis
  1. (CDK1|​Y14/15_pho|​T161_pho:​CyclinA1*)|​active@default map


References
PMID:17243194
53BP1* binds to DNA and stops DNA resection and therefore stops HR during cell cycle except S-phase, because 53BP1* is phosphorylated by CDK1(CDC2) during S-phase, this phosphorylation inhibits 53BP1* activity.

Confidence
REF=1 FUNC=4