Reaction transcription d_re232 map

gBRCA1@default map → rBRCA1@default map

Reaction regulators:
Catalysis
  1. BRIT1*@default map
  2. BRIT1*:​E2F1@default map


References
p53 inhibits BRCA1 expression, this is a negative loop as response to the up-regulation and stabilization of p53 by BRCA1:
PMID:10884389, PMID:12496474
BRIT1*/E2F1 complex activates BRCA1 and CHEK1 transcription during S-phase and G2/M checkpoints:
PMID:15220350, PMID:18660752

Confidence
REF=3 FUNC=5