Reaction state_transition re82 map

RIP1|​ubi:​TNFalpha:​TRADD:​TRAF2:​cIAP1/2@Cytoplasm map → MEKK1@Cytoplasm map

No reaction regulators




PMID:9808624. Xia Y, Wu Z, Su B, Murray B, Karin M.JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension.Genes Dev. 1998 Nov 1;12(21):3369-81.
PMID:9244310. Regnier CH, Song HY, Gao X, Goeddel DV, Cao ZD, Rothe MTitle: Identification and characterization of an I kappa B kinase.CELL 90 (2): 373-383 JUL 25 1997
PMID:8898208.Liu ZG, Hsu H, Goeddel DV, Karin M.Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death. Cell. 1996 Nov 1;87(3):565-76.