Reaction state_transition re125 map

TNFR1@Cytoplasm map + cIAP1/2@Cytoplasm map + TRAF2@Cytoplasm map + RIP1|​ubi@Cytoplasm map → RIP-1|​ubi:​TNFR1:​TNFalpha:​TRADD:​TRAF2:​cIAP1/2@Cytoplasm map

No reaction regulators




PMID:8943045.Hong-Bing Shu, Masahiro Takeuchi, and David V. Goeddel.The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. Proc. Natl. Acad. Sci. USA Vol. 93, pp. 13973-13978, November 1996.
PMID:9529147. Kelliher MA, Grimm S, Ishida Y, Kuo F, Stanger BZ, Leder P.The death domain kinase RIP mediates the TNF-induced NF-kappaB signal.Immunity. 1998 Mar;8(3):297-303.