Reaction state_transition re138 map

TNFR1:​TNFalpha:​TRADD:​TRAF2@Cytoplasm map → (IKKE:​TANK:​TBK1)|​active@Cytoplasm map

No reaction regulators




PMID:10759890.Nomura F, Kawai T, Nakanishi K, Akira S.NF-kappaB activation through IKK-i-dependent I-TRAF/TANK phosphorylation. Genes Cells. 2000 Mar;5(3):191-202
PMID:8608943.Cheng G, Baltimore D.TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation. Genes Dev. 1996 Apr 15;10(8):963-73
PMID:10581243 Pomerantz JL, Baltimore D.NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase.EMBO J. 1999 Dec 1;18(23):6694-704.