Reaction state_transition re168 map

MD2:​TICAM-2:​TLR4:​TRIF@Cytoplasm map + RIP1@Cytoplasm map → MD2:​RIP1:​TICAM-2:​TLR4:​TRIF@Cytoplasm map

No reaction regulators




PMID:12471095.Yamamoto M, Sato S, Mori K, Hoshino K, Takeuchi O,Takeda K, Akira S.A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling.
PMID:14556004.Yamamoto M, Sato S, Hemmi H, Uematsu S, Hoshino K, Kaisho T, Takeuchi O, Takeda K, Akira S. TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway.Nat Immunol. 2003 Nov;4(11):1144-50.
PMID:11976338.Re F, Strominger JL. Monomeric recombinant MD-2 binds toll-like receptor 4 tightly and confers lipopolysaccharide responsiveness.J Biol Chem. 2002 Jun 28;277(26):23427-32. Epub 2002 Apr 25.