Reaction state_transition re178
MYD88:TIRAP:TLR2@Cytoplasm
+ IRAK1@Cytoplasm
+ IRAK4@Cytoplasm
→ IRAK1:IRAK4:MYD88:TIRAP:TLR1:TLR2@Cytoplasm
No reaction regulators
PMID:12447441.Yamamoto M, Sato S, Hemmi H, Sanjo H, Uematsu S, Kaisho T, Hoshino K, Takeuchi O, Kobayashi M, Fujita T, Takeda K, Akira S.Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature. 2002 Nov 21;420(6913):324-9.