Reaction state_transition re179
IRAK1:IRAK4:MYD88:TIRAP:TLR1:TLR2@Cytoplasm
→ IRAK1|pho|pho|pho@Cytoplasm
Reaction regulators:
- Catalysis
- IRAK1:IRAK4:MYD88:TIRAP:TLR1:TLR2@Cytoplasm
- Inhibition
- IRAK-M@Cytoplasm
PMID:12150927.Kobayashi K, Hernandez LD, Galan JE, Janeway CA Jr, Medzhitov R, Flavell RA.IRAK-M is a negative regulator of Toll-like receptor signaling. Cell. 2002 Jul 26;110(2):191-202.