Reaction state_transition re185 map

IRAK1:​IRAK4:​TIRAP:​TLR5@Cytoplasm map → IRAK1|​pho|​pho|​pho@Cytoplasm map

No reaction regulators




PMID:11323673.Hayashi F, Smith KD, Ozinsky A, Hawn TR, Yi EC, Goodlett DR, Eng JK, Akira S, Underhill DM, Aderem A.The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature. 2001 Apr 26;410(6832):1099-103.
PMID:12702497.Yu Y, Zeng H, Lyons S, Carlson A, Merlin D, Neish AS, Gewirtz AT. TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism. Am J Physiol Gastrointest Liver Physiol. 2003 Aug;285(2):G282-90. Epub 2003 Apr 17.
PMID:15324458.Tallant T,Deb A,Kar N, Lupica J,de Veer MJ,DiDonato JA.Flagellin acting via TLR5 is the major activator of key signaling pathways leading to NF-kappa B and proinflammatory gene program activation in intestinal epithelial cells.BMC Microbiol. 2004 Aug 23;4:33.