Reaction state_transition re192 
IKK1:IKK2:NEMO@Cytoplasm → IKK1:IKK2:NEMO|ubi@Cytoplasm
Reaction regulators:
- Catalysis
- MEKK3@Cytoplasm
PMID:16737960.Qin J, Yao J, Cui G, Xiao H, Kim TW, Fraczek J, Wightman P, Sato S, Akira S, Puel A, Casanova JL, Su B, Li X.TLR8-mediated NF-kappaB and JNK activation are TAK1-independent and MEKK3-dependent.J Biol Chem. 2006 Jul 28;281(30):21013-21. Epub 2006 May 31.