Reaction state_transition re296
TLR9@Endosome
+ MYD88@Cytoplasm
+ IRAK1@Cytoplasm
+ IRAK4@Cytoplasm
→ IRAK1:IRAK4:MYD88:TLR9@Endosome
No reaction regulators
PMID:15207506 Wagner H. The immunobiology of the TLR9 subfamily. Trends Immunol. 2004 Jul;25(7):381-6.
PMID:11607032 Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.
Nature. 2001 Oct 18;413(6857):732-8.