Reaction state_transition re326
TRIF@Cytoplasm
→ degraded
Reaction regulators:
- Catalysis
- A20@Cytoplasm
PMID:15474016 Wang YY, Li L, Han KJ, Zhai Z, Shu HB
A20 is a potent inhibitor of TLR3- and Sendai virus-induced activation of NF-kappaB and ISRE and IFN-beta promoter. FEBS Lett. 2004 Oct 8;576(1-2):86-90
PMID:16306043 Lin R, Yang L, Nakhaei P, Sun Q, Sharif-Askari E, Julkunen I, Hiscott J.
Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20. J Biol Chem. 2006 Jan 27;281(4):2095-103