Protein SOS* map

Identifiers
HUGO:SOS1 HGNC:11187 ENTREZ:6654 UNIPROT:Q07889 GENECARDS:SOS1 HUGO:SOS2 HGNC:11188 ENTREZ:6655 UNIPROT:Q07890 GENECARDS:SOS2

Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS

References
son of sevenless homolog 1 (Drosophila)
REACTOME:64848 KEGG:6654 ATLASONC:GC_SOS1 WIKI:SOS1
son of sevenless homolog 2 (Drosophila)
REACTOME:64850 ATLASONC:GC_SOS2 WIKI:SOS2
GINGF "gingival fibromatosis hereditary 1"
"son of sevenless (Drosophilia) homolog 2"
 NATURAL_KILLER  map
CASCADE:Fc_gamma_RIII
PMID:8551221
CD16 and IL-2R Triggering Activate p21RAS in Human NK Cells via LAT/SHC/GRB2/sos pathway.
Phosphorylated Shc interacts with Grb2, which, in turn, interacts with Sos.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. SOS*@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. SOS*@INNATE_IMMUNE_CELL_Cytosol map → map SOS*@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. GDP:​HRAS@INNATE_IMMUNE_CELL_Cytosol map + GTP@INNATE_IMMUNE_CELL_Cytosol map → map GTP:​HRAS@INNATE_IMMUNE_CELL_Cytosol map + GDP@INNATE_IMMUNE_CELL_Cytosol map