Protein GAS6 map

Identifiers
HUGO:GAS6

Maps_Modules
MODULE:INPUT_ACTIVATORS MODULE:TUMOR_RECOGNTITON MODULE:DANGER_SIGNAL_PATHWAYS

References
 MACROPHAGE  map
CASCADE:MERTK
PMID:19631584
The Mer receptor tyrosine kinase is expressed on discrete macrophage subpopulations and mainly uses Gas6 as its ligand for uptake of apoptotic cells.
PMID:25695599
Mer receptor tyrosine kinase mediates both tethering
and phagocytosis of apoptotic cells downstream of PROS1 and Gas6

Modifications:
In compartment: TUMOR_CELL_AS_INDUCTOR_Membrane
  1. GAS6@TUMOR_CELL_AS_INDUCTOR_Membrane map
Participates in complexes:
In compartment: default
  1. GAS6:​PtdSer@default map
Participates in reactions:
As Reactant or Product:
  1. PtdSer@TUMOR_CELL_AS_INDUCTOR_Membrane map + GAS6@TUMOR_CELL_AS_INDUCTOR_Membrane map → map GAS6:​PtdSer@default map
As Catalyser:
  1. MERTK@INNATE_IMMUNE_CELL_Membrane map → map MERTK@INNATE_IMMUNE_CELL_Membrane map