Protein CD11c* map

Identifiers
HUGO:ITGAX

Maps_Modules
MODULE:MARKERS_DC MODULE:MARKERS_NEUTROPHIL MODULE:INPUT_ACTIVATORS MODULE:TUMOR_RECOGNTITON MODULE:INTEGRINS MODULE:DANGER_SIGNAL_PATHWAYS

References
 DENDRITIC_CELL  map
 MACROPHAGE  map
CASCADE:MIF
CASCADE:CR4
CASCADE:FLT3LG
CASCADE:IFNAB
PMID:15573129
CD11c is a maker of myeloid DCs.
PMID:8920882
FLT3 ligand upregulates surface expression of CD11c in DCs.
PMID:23390297
MIF inhitits expression of M1 markers such as TNF, IL12p40, COX2, INOS, IRF-5, MHC-II, CD11c, CD80, CD86 and MIF induces expression of M2 markers as IL10, stabilin-1, MRC-1, CD206, CD23
PMID: 11207245
I IFN receptor signaling regulates antigen cross-presentation to CD8(+) T cells. (), probably via upregulation of CD80, CD86, CD40, CD83 and MHC class II and CD11c,
PMID:17513775
Probably via STAT1(demondrtated for CD40 and CD11c PMID:14764699, and for CD40, CD80, CD86, and MHC II  )

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. CD11c*@INNATE_IMMUNE_CELL_Cytosol map
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CD11c*@INNATE_IMMUNE_CELL_Membrane map
In compartment: MARKERS_DC
  1. CD11c*@MARKERS_DC map
In compartment: MARKERS_NEUTROPHIL
  1. CD11c*@MARKERS_NEUTROPHIL map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CD11c*:​CD18*@INNATE_IMMUNE_CELL_Membrane map
  2. CD11c*:​CD18*:​iC3b*@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. CD11c*@INNATE_IMMUNE_CELL_Cytosol map → map CD11c*@INNATE_IMMUNE_CELL_Membrane map
  2. CD11c*:​CD18*:​iC3b*@INNATE_IMMUNE_CELL_Membrane map → map EXOCYTOSIS_AND_PHAGOCYTOSIS@INNATE_IMMUNE_CELL_Membrane map
  3. rCD11c*@MARKERS_DC map → map CD11c*@MARKERS_DC map
  4. CD18*@INNATE_IMMUNE_CELL_Membrane map + CD11c*@INNATE_IMMUNE_CELL_Membrane map → map CD11c*:​CD18*@INNATE_IMMUNE_CELL_Membrane map
  5. iC3b*@default map + CD11c*:​CD18*@INNATE_IMMUNE_CELL_Membrane map → map CD11c*:​CD18*:​iC3b*@INNATE_IMMUNE_CELL_Membrane map
As Catalyser: