Protein B7H3* map

Identifiers
HUGO:CD276

Maps_Modules
MODULE:IMMUNOSUPPRESSIVE_CHEKPOINTS MODULE:IMMUNE_SUPPRESSION MODULE:EFFECTOR_INHIBITION

References
 DENDRITIC_CELL  map
PMID:17615586, PMID:15294965
After contact to Treg, DC up-regulate the inhibitory B7-H3 molecule and display reduced numbers of MHC–peptide complexes, leading to impaired T cell stimulatory function.
B7-H3 plays a significant role in suppressing T cell activation by Treg-exposed DC.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. B7H3*@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. B7H3*@INNATE_IMMUNE_CELL_Cytosol map → map Immune_checkpoints_T_cells_Inhibitors@INNATE_IMMUNE_CELL_Membrane map
    As Catalyser: