Protein PXN
References
CASCADE:NKG2D
PMID:18287025
JNK induces assosiation of Paxilin with MTOC resulted in polarization of the MTOC and cytolytic granules, and finally exocytosis of cytolytic proteins downstream of NKG2D.
Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- PXN@INNATE_IMMUNE_CELL_Cytosol
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- PXN:TUBGCP2:TUBGCP3:TUBGCP4:TUBGCP5:TUBGCP6:Tubulin-_alpha_*:Tubulin-_beta_*:Tubulin-_gamma_*@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- TUBGCP2:TUBGCP3:TUBGCP4:TUBGCP5:TUBGCP6:Tubulin-_alpha_*:Tubulin-_beta_*:Tubulin-_gamma_*@INNATE_IMMUNE_CELL_Cytosol
+ PXN@INNATE_IMMUNE_CELL_Cytosol
→
PXN:TUBGCP2:TUBGCP3:TUBGCP4:TUBGCP5:TUBGCP6:Tubulin-_alpha_*:Tubulin-_beta_*:Tubulin-_gamma_*@INNATE_IMMUNE_CELL_Cytosol
- PXN:TUBGCP2:TUBGCP3:TUBGCP4:TUBGCP5:TUBGCP6:Tubulin-_alpha_*:Tubulin-_beta_*:Tubulin-_gamma_*@INNATE_IMMUNE_CELL_Cytosol
→
MTOC_polarization@INNATE_IMMUNE_CELL_Cytosol
As Catalyser: