Identifiers
HUGO:CX3CR1
Maps_Modules
MODULE:INPUT_ACTIVATORS MODULE:TUMOR_RECOGNTITON MODULE:DANGER_SIGNAL_PATHWAYS MODULE:RECRUITMENT_OF_IMMUNE_CELLS
References
DENDRITIC_CELL
NATURAL_KILLER
MACROPHAGE
CASCADE:CX3CR1
PMID:12455035
CX3CL1 induces chemoattraction and activation of DC via CX3CR1 and induces Tcell activation. Adherence of DC to cells expressed CX3CL1 resulted in phenotypic maturation and upregulated IL-12 secretion of DC, and more strong stimulation of allogeneic T-cell proliferation by DC
PMID:11766992
Fractalkine induces chemotaxis and migration associated actin polymerization in immature as well as in mature DCs