Antisense RNA MIR183 map

Identifiers
HUGO:MIR183

Maps_Modules
MODULE:INPUT_ACTIVATORS MODULE:TUMOR_RECOGNTITON MODULE:NK_ACTIVATING_RECEPTORS MODULE:CORE_SIGNALING_PATHWAYS MODULE:MIRNA_TF_IMMUNOSUPPRESSIVE

References
 NATURAL_KILLER  map
CASCADE:TGFB
PMID:24586048
Suppression of NK cells is a result of TGF-β induction of microRNA (miR)-183, which binds and represses DNAX activating protein 12 kDa (DAP12), a signal adaptor for lytic function in NK cells.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. arMIR183@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. DAP12*:​MIR183@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. gMIR183@INNATE_IMMUNE_CELL_Cytosol map → map arMIR183@INNATE_IMMUNE_CELL_Cytosol map
  2. DAP12*:​MIR183@INNATE_IMMUNE_CELL_Cytosol map → map degraded
  3. rDAP12*@INNATE_IMMUNE_CELL_Cytosol map + arMIR183@INNATE_IMMUNE_CELL_Cytosol map → map DAP12*:​MIR183@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser: