Protein IL12p35* map

Identifiers
HUGO:IL12A

Maps_Modules
 MACROPHAGE  map
MODULE:INPUT_ACTIVATORS
MODULE:IMMUNE_STIMULATION
MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS
MODULE:EFFECTOR_ACTIVATION
MODULE:IMMUNOSTIMULATORY_CYTOKINE_EXPRESSION
CASCADE:TLR2_4
CASCADE:CSF2

References
PMID:21240265
High expression of IRF5 was characteristic of M1 macrophages, in which it directly activated transcription of the genes encoding interleukin 12 subunit p40 (IL-12p40), IL-12p35 and IL-23p19 and repressed the gene encoding IL-10.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. IL12p35*@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. IL12p35*@INNATE_IMMUNE_CELL_Cytosol map → map IL12*@INNATE_IMMUNE_CELL_Cytosol map
    2. rIL12p35*@INNATE_IMMUNE_CELL_Cytosol map → map IL12p35*@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: