Protein ABL1
Identifiers
HUGO:ABL1
Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:IMMUNOSUPPPRESSIVE_CORE_PATHWAYS
References
CASCADE:KIR2DL1
CASCADE:NKG2A
NATURAL_KILLER
PMID:18835194
Association of CrkII with ALBL1(c-Abl) occurred during inhibition. ABL1 phosphorylates CRK and inhibits CRK activity downstream of KIR2DL1 and NKG2A/CD94 pathway..
Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- ABL1@INNATE_IMMUNE_CELL_Cytosol
Participates in complexes:
Participates in reactions:
As Reactant or Product:- ABL1@INNATE_IMMUNE_CELL_Cytosol
→
ABL1@INNATE_IMMUNE_CELL_Cytosol
As Catalyser:- (BCAR1|pho:CBL|pho:CRK:CRKL:RAPGEF1)|active@INNATE_IMMUNE_CELL_Cytosol
→
BCAR1|pho:CBL|pho:CRKL|pho:CRK|pho:RAPGEF1@INNATE_IMMUNE_CELL_Cytosol