Protein ALOX15 map

Identifiers
HUGO:ALOX15
CASCADE:IL4
CASCADE:IL13

Maps_Modules
 MACROPHAGE  map
MODULE:CORE_SIGNALING_PATHWAYS
MODULE:IMMUNOSUPPPRESSIVE_CORE_PATHWAYS

References
PMID:10432118
ALOX15 activation results in induction of CD36 expression downstream of IL4 and IL13 via PRARG
Linoleic acid is oxygenated by ALOX15 to 13-HODE which activates PPARG.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. ALOX15@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rALOX15@INNATE_IMMUNE_CELL_Cytosol map → map ALOX15@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. linoleic acid@INNATE_IMMUNE_CELL_Cytosol map → map 13(S)-HPODE@INNATE_IMMUNE_CELL_Cytosol map