Identifiers
HUGO:WNT7B
Maps_Modules
MODULE:EFFECTOR_INHIBITION MODULE:TUMOR_GROWTH MODULE:ANGIOGENIC_FACTORS MODULE:GROWTH_FACTORS_EXPRESSION
References
MDSC
PMID:24638982
we found tumor progression relied upon WNT7B produced by myeloid cells in the microenvironment. Wnt7b deletion in myeloid cells reduced the mass and volume of tumors due to a failure in the angiogenic switch.