Protein ADM map

Identifiers
HUGO:ADM

Maps_Modules
MODULE:EFFECTOR_INHIBITION MODULE:TUMOR_GROWTH MODULE:ANGIOGENIC_FACTORS

References
 MACROPHAGE  map
PMID:21994414
ADM was expressed by infiltrating TAMs in human melanoma, and its secretion from macrophages was upregulated upon coculture with melanoma cells, or with melanoma cells conditioned media. Meanwhile, TAMs enhanced endothelial cell migration and tubule formation and also increased B16/F10 tumor growth. Neutralizing ADM antibody and ADM receptor antagonist, AMA, attenuated TAM-induced angiogenesis in vitro and melanoma growth in vivo, respectively.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. ADM@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. ADM@INNATE_IMMUNE_CELL_Cytosol map → map ANGIOGENESIS@default map
    As Catalyser: