Maps_Modules
MODULE:TUMOR_KILLING MODULE:EFFECTOR_ACTIVATION MODULE:EXOCYTOSIS_AND_PHAGOCYTOSIS
References
PMID:19741094, PMID:19741094
t Cdc42 is essential for the activation of WASP and N-WASP, leading to actin assembly and phagocytic cup formation by macrophages during Fc(gamma)R-mediated phagocytosis.
WASP was required for actin polymerization, whereas N-WASP was required for pseudopod protrusion.
Cdc42 Is Required for Activation and Tyrosine Phosphorylation of WASP/N-WASP