Gene HLX map

Identifiers
HUGO:HLX

Maps_Modules
MODULE:CORE_SIGNALING_PATHWAYS MODULE:MIRNA_TF_IMMUNOSTIMULATORY

References
 NATURAL_KILLER  map
PMID:12055627, PMID:14614857
T-Bet induces HLX in T cells, and probably in NK cells.
GATA-3-deficient NK cells produced less IFN-γ compared to control NK cells.
T-bet expression was approximately 4-fold reduced in GATA-3° NK cells compared to controls, while Hlx expression was about 10-fold reduced (provavly via T-bet).

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. gHLX@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gHLX@INNATE_IMMUNE_CELL_Cytosol map → map rHLX@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: