Protein OX40L* map

Identifiers
HUGO:TNFSF4

Maps_Modules
MODULE:IMMUNE_STIMULATION MODULE:IMMUNOSTIMULATORY_CHEKPOINTS MODULE:EFFECTOR_ACTIVATION

References
 DENDRITIC_CELL  map
 NEUTROPHIL  map
CASCADE:IL3
CASCADE:CD40LG
PMID:9378971, PMID:10626891
OX40L is expressed on DCs surface after CD40 stimulation.
Ox40L-deficient dendritic cells are defective in costimulating T cell cytokine production.
PMID: 17200410, PMID:23125331, PMID:15034038
pDCs stimulated with IL-3 plus CD40L induce production ICOS-L and expression of OX40L.
PMID:24778133
Plasmacytoid Dendritic Cells Support Melanoma Progression by Promoting Th2 and Regulatory Immunity through OX40L and ICOSL .
PMID:25384214
TANs enhance T cell proliferation by direct cell-cell signaling, likely due to the OX40L/OX40 and 4-1BBL/4-1BB pathways.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. OX40L*@INNATE_IMMUNE_CELL_Cytosol map
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. OX40L*@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. OX40L*@INNATE_IMMUNE_CELL_Cytosol map → map OX40L*@INNATE_IMMUNE_CELL_Membrane map
    2. OX40L*@INNATE_IMMUNE_CELL_Membrane map → map Immune_checkpoints_T_cells_Activators@default map
    As Catalyser: