Protein HGF map

Identifiers
HUGO:HGF

Maps_Modules
MODULE:EFFECTOR_INHIBITION MODULE:TUMOR_GROWTH MODULE:ANGIOGENIC_FACTORS MODULE:GROWTH_FACTORS_EXPRESSION

References
 MACROPHAGE  map
 NEUTROPHIL  map
PMID:18633355
Hypoxia induces a distinct pro-angiogenic phenotype in human macrophages in vitro42, 43 including the upregulation of VEGF, bFGF, CXCL8, COX2, hepatocyte growth factor (HGF), VEGFR1, tissue factor (F3) and MMP12.
PMID:16212809
HGF drives tumor growth
PMID:26819959, PMID:12649206
Neutrophiles produce HGF and induce tumor growth
High HGF levels in BALF supernatants were significantly associated with poorer outcome in patients with BAC

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. HGF@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. HGF@INNATE_IMMUNE_CELL_Cytosol map → map ANGIOGENESIS@default map
    2. HGF@INNATE_IMMUNE_CELL_Cytosol map → map TUMOR_GROWTH@TUMOR_CELL_AS_EFFECTOR map
    As Catalyser: