Gene IL23A map

Identifiers
HUGO:IL23A

Maps_Modules
 MACROPHAGE  map
MODULE:EFFECTOR_INHIBITION
MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_EXPRESSION
MODULE:IMMUNE_SUPPRESSION
CASCADE:TLR2_4
CASCADE:CSF2
CASCADE:CSF1
CASCADE:IL13
CASCADE:IL4
PMID:24204259
IL4RA signaling upregulates IL18 expression and downregulates IL10 expression and also mRNA expression of IL-23p19 and INHBA (activin A), cytokines previously implicated in promoting Th2 responses

References
PMID:11477091
TLR2 stimulation additionally resulted in preferential induction of IL-8 and p19/IL-23. ()
PMID:17404308
CSF1 downregulates TNF, IL-23p19, IL-12p40 expression probably via induction of acomulation of p50 homodimer and inhibition of p65/p50 NF-kB signaling.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. gIL23A@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gIL23A@INNATE_IMMUNE_CELL_Cytosol map → map rIL23A@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: