Gene IL8* map

Identifiers
HUGO:CXCL8

Maps_Modules
 MACROPHAGE  map
 NATURAL_KILLER  map
MODULE:EFFECTOR_INHIBITION
MODULE:TUMOR_GROWTH
MODULE:ANGIOGENIC_FACTORS
CASCADE:INTEGRIN_A4B1
CASCADE:INTEGRIN_A5B1
CASCADE:TLR2_4

References
PMID:17485448
Inhibition of‭ ‬NFkB signaling downstream of‭ ‬ABIN3‭ ‬
inhibits expression of‭ ‬IL8,‭ ‬IL6,‭ ‬TNF,‭ ‬IL12
PMID:10661401
Cross-Linking of β1 Integrins on Human NK Cells via VAV1 activates Rac1, which controls p38 MAPK Activation. MKK3 is activated by β1 Integrin Cross-Linking on Human NK Cells,
It activates p38MAPK regulated IL8 mRNA expression and protein production by NK cells downstream of integrin signaling

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. gIL8*@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gIL8*@INNATE_IMMUNE_CELL_Cytosol map → map rIL8*@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: