Identifiers
HUGO:CCL2
Maps_Modules
MACROPHAGE
MDSC
NEUTROPHIL
MODULE:RECRUITMENT_OF_IMMUNE_CELLS
CASCADE:TGFB
CASCADE:CSF1
References
PMID:18776941
Expression of VEGF and bFGF, but also IL-1β, MMP9, CCL2, and CXCL2 is STAT3-dependent in myeloid cells.
PMID:19732719
Inhibition of TGF-ß signaling downregulates Arginase1, CCL5 and CCL2 expression and upregulates TNF, ICAM1,CCL3 expression (mRNA) in tumor neutrophiles (TAN)
PMID:17404308
CSF1 induces IL10 and CCL2 mRNA expression in macrophages
Stat3 activity is required for tumor factor–induced migration of ECs