Gene IRF1 map

Identifiers
HUGO:IRF1

Maps_Modules
 MACROPHAGE  map
 NATURAL_KILLER  map
MODULE:CORE_SIGNALING_PATHWAYS
MODULE:MIRNA_TF_IMMUNOSTIMULATORY
CASCADE:IL2
CASCADE:TNF
CASCADE:IFNAB
CASCADE:IFNG

References
PMID:12433365
INFG induces SOCS1 expression in macrophages.
PMID:10820262
Probably IFNG induces SOCS1 expressiov via IRF1 upregulation downstream of STAT1
PMID:18345002
TNF induces IRF1 expression both through TNFR1 and TNFR2.
TNF induced IFNB expression through IRF1
PMID:10358173, PMID:7479881
IL2 signaling induces IRF1 expression in NK cells, probably via STAT5 (
PMID:17985330
IFN-β induces IRF1 expression, probably via STAT1in DCs.()

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. gIRF1@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gIRF1@INNATE_IMMUNE_CELL_Cytosol map → map rIRF1@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: