Gene IRAK3 map

Identifiers
HUGO:IRAK3

Maps_Modules
 MACROPHAGE  map
MODULE:CORE_SIGNALING_PATHWAYS
MODULE:IMMUNOSTIMULATORY_CORE_PATHWAYS
CASCADE:TGFB

References
PMID:12150927
IRAK3 (IRAK-M) is a negative regulator of Toll-like receptor signaling
in macrophages. It prevented dissociation of IRAK and IRAK-4 from MyD88 and formation of IRAK-TRAF6 complexes.
PMID:21278795
TGFB-induced IRAK3 (IRAK-M) expression in tumor-associated macrophages
and inhibit TLR-dependent signaling

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. gIRAK3@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gIRAK3@INNATE_IMMUNE_CELL_Cytosol map → map rIRAK3@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: