Gene IL2RA map

Identifiers
HUGO:IL2RA

Maps_Modules
MODULE:INPUT_ACTIVATORS MODULE:IMMUNE_STIMULATION MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS

References
 NATURAL_KILLER  map
 DENDRITIC_CELL  map
CASCADE:IL2
CASCADE:IL15
CASCADE:IL21
PMID:24829413
STAT5 is phosphorylated downstream IL2, It upregulate the promoter activity of both IL2RA and IFNG in dendritic cells downstream of IL2
PMID:12244150
Both IL-15 and IL-21 up-regulated the expression of the IL-2Rα IL-12Rβ2 IL-18Rα and IL-18Rβ in NK cells ().

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. gIL2RA@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gIL2RA@INNATE_IMMUNE_CELL_Cytosol map → map rIL2RA@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: