Phenotype JAK_minus_STAT cascade map
JAK_minus_STAT cascade@microglia
Symbol:
Name: JAK-STAT cascade
Description:
Previous Symbols:
Synonyms:
Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The JAK-STAT cascade begins with activation of STAT proteins by members of the JAK family of tyrosine kinases, proceeds through dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins.
Modifications:
In compartment: microglia
  1. JAK_minus_STAT cascade@microglia map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. JAK_minus_STAT cascade@microglia map → map s11102
    2. IFNGR1:​IFNGR2:​JAK1:​JAK2@microglia map → map JAK_minus_STAT cascade@microglia map
    As Catalyser: