Complex APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:BUB1:BUB3:BUBR1*:CDC20:MAD1*:MAD2* 
Complex composition:
- CDC20
- MAD2*
- BUB3
- BUBR1*
- MAD1*
- BUB1
- APC4*
- APC7*
- APC8*
- APC12*
- APC5*
- APC2*
- APC6*
- APC3*
- APC1*
- APC10*
- APC11*
APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:BUB1|pho:BUB3:BUBR1*:CDC20:MAD1*|pho:MAD2*@default
Identifiers
NAME:APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:BUB1:BUB3:BUBR1*:CDC20:MAD1*:MAD2*
References
d_re216( dnarepair ):
By CDC20/APC complex:
M to G1 transition
By Mitotic checkpoint complex:
Spindle checkpoint
PARP3 activated spindle checkpoint
PMID:21270334
Tankyrase activated spindle checkpoint
PMID:23197039
d_re385:( dnarepair ) Separin is inhibited by Securin
Confidence
REF=1 FUNC=4
Modifications:
Participates in complexes:
In compartment: default
- APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:BUB1|pho:BUB3:BUBR1*:CDC20:MAD1*|pho:MAD2*@default
Participates in reactions:
As Reactant or Product:- APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:CDC20@default + MAD2*@default + BUBR1*@default + BUB3@default + MAD1*|pho@default + BUB1|pho@default → APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:BUB1|pho:BUB3:BUBR1*:CDC20:MAD1*|pho:MAD2*@default
- APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:BUB1|pho:BUB3:BUBR1*:CDC20:MAD1*|pho:MAD2*@default → APC1*:APC10*:APC11*:APC12*:APC2*:APC3*:APC4*:APC5*:APC6*:APC7*:APC8*:CDC20@default + BUB3@default + BUBR1*@default + MAD2*@default + MAD1*|pho@default + BUB1|pho@default
As Catalyser:- M phase@default → G1 phase@default
- Separin*@default + Securin*@default → Securin*:Separin*@default
- SCC1*@default + STAG*@default + SMC3@default + SMC1*@default → SCC1*:SMC1*:SMC3:STAG*@default