Reaction state_transition d_re129 map

Ku80*@default map → Ku80*|​ubi@default map

Reaction regulators:
Catalysis
  1. MDC1|​pho:​RNF8@default map


References
PMID:18809224
Complex RNF8:MDC1 ubiquitinates Ku80 and causes it's dissociation from DNA and degradation.This bring to shift from C_NHEJ to HR:
PMID:18001825, PMID:18678709

Confidence
REF=2 FUNC=5