Reaction state_transition d_re168 map

PCNA@default map → PCNA|​K164_ubi@default map

Reaction regulators:
Catalysis
  1. RAD18:​RAD6*@default map


References
PMID:18157158
Ubiquitination of PCNA by RAD6-RAD18 increases affinity of PCNA to POLH and makes switch from PCNA-POLD to PCNA-POLH and stops translation and initiates TLS pathway
PMID:15280666, PMID:18498753

Confidence
REF=1 FUNC=5