Reaction state_transition d_re194 map

FANCM@default map → FANCM|​pho@default map

Reaction regulators:
Catalysis
  1. PLK1|​pho|​active@default map
Trigger
  1. G2 phase@default map


References
FANCM is phosphorylated by PLK1 and ubiquitinated by beta-TRCP (in the SCF complex) in response to G2/M checkpoint. Phosphorylated FANCM is degraded and FANCONI pathway is inhibited during mitosis.
PMID:19270156, PMID:19686080

Confidence
REF=1 FUNC=2