Reaction state_transition re116 
MEKK3@Cytoplasm → MEKK3|pho|active@Cytoplasm
Reaction regulators:
- Catalysis
- (TAB1:TAB2:TAK1 |pho:TRAF6)|active@Cytoplasm
PMID:16260783.Blonska M, Shambharkar PB, Kobayashi M, Zhang D, Sakurai H, Su B, Lin X. TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation. J Biol Chem. 2005 Dec 30;280(52):43056-63.