Reaction state_transition re118 map

RIP1|​ubi:​TNFalpha:​TRADD:​TRAF2:​cIAP1/2@Cytoplasm map → (TAB1:​TAB2:​TAK1 |​pho:​TRAF6)|​active@Cytoplasm map

No reaction regulators




PMID:16260783.Blonska M, Shambharkar PB, Kobayashi M, Zhang D, Sakurai H, Su B, Lin X. TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation. J Biol Chem. 2005 Dec 30;280(52):43056-63.