Phenotype Wnt stimulation
Modifications:
In compartment: Cell membrane
- Wnt stimulation@Cell membrane
Participates in complexes:
Participates in reactions:
As Reactant or Product:
As Catalyser:- Axin:GSK3alpha/beta@Cell membrane
+ Dishevelled:Frizzled :G proteins:LRP5/6:Wnt@Cell membrane
→
Axin:Dishevelled:Frizzled :G proteins:GSK3alpha/beta:LRP5/6:Wnt@Cell membrane
- _beta_Catenin@Cell membrane
→
_beta_Catenin@Nucleus
- Axin:GSK3alpha/beta@Cell membrane
→
Axin|S322_pho|S326_pho|S330_pho|T609_pho|S614_pho:GSK3alpha/beta@Cell membrane
- APC:Axin|S322_pho|S326_pho|S330_pho|T609_pho|S614_pho:CK1:GSK3alpha/beta:_beta_Catenin@Cell membrane
→
APC:Axin:CK1:GSK3alpha/beta:_beta_Catenin@Cell membrane
- Axin|S322_pho|S326_pho|S330_pho|T609_pho|S614_pho:GSK3alpha/beta:TSC1:TSC2|S1345_pho|S1337_pho|S1341_pho@Endomembrane
→
TSC1@Endomembrane
+ TSC2|S1345_pho|S1337_pho|S1341_pho@Cell membrane
- Axin|S322_pho|S326_pho|S330_pho|T609_pho|S614_pho:GSK3alpha/beta:TSC1:TSC2|S1345_pho|S1337_pho|S1341_pho@Endomembrane
→
TSC2|S1345_pho|S1337_pho|S1341_pho@Cell membrane
+ Axin|S322_pho|S326_pho|S330_pho|T609_pho|S614_pho:GSK3alpha/beta@Cell membrane