Reaction unknown_transition re333 map

TSC2|​S981_pho|​S939_pho|​T1462_pho@Cell membrane map → TSC2@Cell membrane map

No reaction regulators




PMID:18198340
In response to hypoxia, REDD1 is induced and binds 14-3-3, resulting in TSC2/14-3-3 dissociation, TSC1/2 activation, and mTORC1 inhibition.